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Role of DJ-1 in the mechanism of pathogenesis of Parkinson's disease

DJ-1 protein has multiple specific mechanisms to protect dopaminergic neurons against neurodegeneration in Parkinson's disease. Wild type DJ-1 can acts as oxidative stress sensor and as an antioxidant. DJ-1 exhibits the properties of molecular chaperone, protease, glyoxalase, transcriptional re...

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Detalles Bibliográficos
Autores principales:	Dolgacheva, Ludmila P., Berezhnov, Alexey V., Fedotova, Evgeniya I., Zinchenko, Valery P., Abramov, Andrey Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Mini-Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531411/ https://www.ncbi.nlm.nih.gov/pubmed/31054074 http://dx.doi.org/10.1007/s10863-019-09798-4

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