Cargando…

A toll-like receptor agonist mimicking microbial signal to generate tumor-suppressive macrophages

Switching macrophages from a pro-tumor type to an anti-tumor state is a promising strategy for cancer immunotherapy. Existing agents, many derived from bacterial components, have safety or specificity concerns. Here, we postulate that the structures of the bacterial signals can be mimicked by using...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Yanxian, Mu, Ruoyu, Wang, Zhenzhen, Xing, Panfei, Zhang, Junfeng, Dong, Lei, Wang, Chunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531447/
https://www.ncbi.nlm.nih.gov/pubmed/31118418
http://dx.doi.org/10.1038/s41467-019-10354-2