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A toll-like receptor agonist mimicking microbial signal to generate tumor-suppressive macrophages
Switching macrophages from a pro-tumor type to an anti-tumor state is a promising strategy for cancer immunotherapy. Existing agents, many derived from bacterial components, have safety or specificity concerns. Here, we postulate that the structures of the bacterial signals can be mimicked by using...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531447/ https://www.ncbi.nlm.nih.gov/pubmed/31118418 http://dx.doi.org/10.1038/s41467-019-10354-2 |