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Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps
The human pathogen Helicobacter pylori displays extensive genetic diversity. While H. pylori is known to evolve during infection, population dynamics inside the gastric environment have not been extensively investigated. Here we obtained gastric biopsies from multiple stomach regions of 16 H. pylori...
Autores principales: | Ailloud, Florent, Didelot, Xavier, Woltemate, Sabrina, Pfaffinger, Gudrun, Overmann, Jörg, Bader, Ruth Christiane, Schulz, Christian, Malfertheiner, Peter, Suerbaum, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531487/ https://www.ncbi.nlm.nih.gov/pubmed/31118420 http://dx.doi.org/10.1038/s41467-019-10050-1 |
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