Cargando…
A phase 0 study of the pharmacokinetics, biodistribution, and dosimetry of (188)Re-liposome in patients with metastatic tumors
BACKGROUND: Liposomes are drug nano-carriers that are capable of targeting therapeutics to tumor sites because of enhanced permeability retention (EPR). In several preclinical studies with various tumor-bearing mice models, (188)Re-liposome that has been developed by the Institute of Nuclear Energy...
Autores principales: | Wang, Shyh-Jen, Huang, Wen-Sheng, Chuang, Chi-Mu, Chang, Chih-Hsien, Lee, Te-Wei, Ting, Gann, Chen, Ming-Huang, Chang, Peter Mu-Hsin, Chao, Ta-Chung, Teng, Hao-Wei, Chao, Yee, Chen, Yuh-Min, Lin, Tzu-Ping, Chang, Ya-Jen, Chen, Su-Jung, Huang, Yuan-Ruei, Lan, Keng-Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531516/ https://www.ncbi.nlm.nih.gov/pubmed/31119414 http://dx.doi.org/10.1186/s13550-019-0509-6 |
Ejemplares similares
-
Translating Research for the Radiotheranostics of Nanotargeted (188)Re-Liposome
por: Chang, Chih-Hsien, et al.
Publicado: (2021) -
Biodistribution and pharmacokinetics of (188)Re-liposomes and their comparative therapeutic efficacy with 5-fluorouracil in C26 colonic peritoneal carcinomatosis mice
por: Tsai, Chia-Che, et al.
Publicado: (2011) -
External beam radiotherapy synergizes (188)Re-liposome against human esophageal cancer xenograft and modulates (188)Re-liposome pharmacokinetics
por: Chang, Chih-Hsien, et al.
Publicado: (2015) -
(188)Re-Liposome Can Induce Mitochondrial Autophagy and Reverse Drug Resistance for Ovarian Cancer: From Bench Evidence to Preliminary Clinical Proof-of-Concept
por: Chang, Chia-Ming, et al.
Publicado: (2017) -
Correlation between radioactivity and chemotherapeutics of the (111)In-VNB-liposome in pharmacokinetics and biodistribution in rats
por: Lee, Wen-Chuan, et al.
Publicado: (2012)