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Multiplexed detection of RNA using MERFISH and branched DNA amplification

Multiplexed error-robust fluorescence in situ hybridization (MERFISH) allows simultaneous imaging of numerous RNA species in their native cellular environment and hence spatially resolved single-cell transcriptomic measurements. However, the relatively modest brightness of signals from single RNA mo...

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Detalles Bibliográficos
Autores principales: Xia, Chenglong, Babcock, Hazen P., Moffitt, Jeffrey R., Zhuang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531529/
https://www.ncbi.nlm.nih.gov/pubmed/31118500
http://dx.doi.org/10.1038/s41598-019-43943-8