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Monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy

The oxygenation level of a tissue is an important marker of the health of the tissue and has a direct effect on performance. It has been shown that the blood flow to the paretic muscles of hemiparetic post-stroke patients is significantly reduced compared to non-paretic muscles. It is hypothesized t...

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Autores principales: MasoudiMotlagh, Mohammad, Sugar, Jeffrey J, Azimipour, Mehdi, Linz, Whitney W, Michalak, Gregory, Seo, Na Jin, Ranji, Mahsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531806/
https://www.ncbi.nlm.nih.gov/pubmed/31191919
http://dx.doi.org/10.1177/2055668315614195
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author MasoudiMotlagh, Mohammad
Sugar, Jeffrey J
Azimipour, Mehdi
Linz, Whitney W
Michalak, Gregory
Seo, Na Jin
Ranji, Mahsa
author_facet MasoudiMotlagh, Mohammad
Sugar, Jeffrey J
Azimipour, Mehdi
Linz, Whitney W
Michalak, Gregory
Seo, Na Jin
Ranji, Mahsa
author_sort MasoudiMotlagh, Mohammad
collection PubMed
description The oxygenation level of a tissue is an important marker of the health of the tissue and has a direct effect on performance. It has been shown that the blood flow to the paretic muscles of hemiparetic post-stroke patients is significantly reduced compared to non-paretic muscles. It is hypothesized that hemodynamic activity in paretic muscles is suppressed as compared to non-paretic muscles, and that oximetry can be used to measure this disparity in real-time. In order to test this hypothesis, a custom-made oximetry device was used to measure hemodynamic activity in the forearm extensor muscles in post-stroke patients’ paretic and non-paretic sides and in a control population during three exercise levels calibrated to the subject’s maximum effort. The change in oxygenation (ΔOxy) and blood volume (ΔBV) were calculated and displayed in real-time. Results show no apparent difference in either ΔOxy or ΔBV between control subjects’ dominant and non-dominant muscles. However, the results show a significant difference in ΔOxy between paretic and non-paretic muscles, as well as a significant difference between normalized post-stroke and control data. Further work will be necessary to determine if the observed difference between the paretic and non-paretic muscles changes over the course of physical therapy and can be correlated with functional improvements.
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spelling pubmed-65318062019-06-12 Monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy MasoudiMotlagh, Mohammad Sugar, Jeffrey J Azimipour, Mehdi Linz, Whitney W Michalak, Gregory Seo, Na Jin Ranji, Mahsa J Rehabil Assist Technol Eng Article The oxygenation level of a tissue is an important marker of the health of the tissue and has a direct effect on performance. It has been shown that the blood flow to the paretic muscles of hemiparetic post-stroke patients is significantly reduced compared to non-paretic muscles. It is hypothesized that hemodynamic activity in paretic muscles is suppressed as compared to non-paretic muscles, and that oximetry can be used to measure this disparity in real-time. In order to test this hypothesis, a custom-made oximetry device was used to measure hemodynamic activity in the forearm extensor muscles in post-stroke patients’ paretic and non-paretic sides and in a control population during three exercise levels calibrated to the subject’s maximum effort. The change in oxygenation (ΔOxy) and blood volume (ΔBV) were calculated and displayed in real-time. Results show no apparent difference in either ΔOxy or ΔBV between control subjects’ dominant and non-dominant muscles. However, the results show a significant difference in ΔOxy between paretic and non-paretic muscles, as well as a significant difference between normalized post-stroke and control data. Further work will be necessary to determine if the observed difference between the paretic and non-paretic muscles changes over the course of physical therapy and can be correlated with functional improvements. SAGE Publications 2015-10-29 /pmc/articles/PMC6531806/ /pubmed/31191919 http://dx.doi.org/10.1177/2055668315614195 Text en © The Author(s) 2015 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Article
MasoudiMotlagh, Mohammad
Sugar, Jeffrey J
Azimipour, Mehdi
Linz, Whitney W
Michalak, Gregory
Seo, Na Jin
Ranji, Mahsa
Monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy
title Monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy
title_full Monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy
title_fullStr Monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy
title_full_unstemmed Monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy
title_short Monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy
title_sort monitoring hemodynamic changes in stroke-affected muscles using near-infrared spectroscopy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531806/
https://www.ncbi.nlm.nih.gov/pubmed/31191919
http://dx.doi.org/10.1177/2055668315614195
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