Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes

OBJECTIVE: Genome wide association studies (GWAS) for type 2 diabetes (T2D) have identified genetic loci that often localise in non-coding regions of the genome, suggesting gene regulation effects. We combined genetic and transcriptomic analysis from human islets obtained from brain-dead organ donor...

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Detalles Bibliográficos
Autores principales: Khamis, Amna, Canouil, Mickaël, Siddiq, Afshan, Crouch, Hutokshi, Falchi, Mario, Bulow, Manon von, Ehehalt, Florian, Marselli, Lorella, Distler, Marius, Richter, Daniela, Weitz, Jürgen, Bokvist, Krister, Xenarios, Ioannis, Thorens, Bernard, Schulte, Anke M., Ibberson, Mark, Bonnefond, Amelie, Marchetti, Piero, Solimena, Michele, Froguel, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531807/
https://www.ncbi.nlm.nih.gov/pubmed/30956117
http://dx.doi.org/10.1016/j.molmet.2019.03.004

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