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Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation
We present here the data to support the understanding of the implication of Rap2a GTPase in LPS-induced innate immune response and NF-κB activation. The data presented are related to molecular tools that were generated, acquired, optimized or validated to investigate Rap2a expression, activation and...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531833/ https://www.ncbi.nlm.nih.gov/pubmed/31193517 http://dx.doi.org/10.1016/j.dib.2019.103965 |
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| author | Carvalho, Brener C. Oliveira, Leonardo C. Rocha, Carolina D. Fernandes, Heliana B. Oliveira, Isadora M. Leãõ, Felipe B. Valverde, Thalita M. Rego, Igor M.G. Ghosh, Sankar Silva, Aristóbolo M. |
| author_facet | Carvalho, Brener C. Oliveira, Leonardo C. Rocha, Carolina D. Fernandes, Heliana B. Oliveira, Isadora M. Leãõ, Felipe B. Valverde, Thalita M. Rego, Igor M.G. Ghosh, Sankar Silva, Aristóbolo M. |
| author_sort | Carvalho, Brener C. |
| collection | PubMed |
| description | We present here the data to support the understanding of the implication of Rap2a GTPase in LPS-induced innate immune response and NF-κB activation. The data presented are related to molecular tools that were generated, acquired, optimized or validated to investigate Rap2a expression, activation and its effects in mammalian cells including RAW264.7 macrophages and THP-1 monocytes under inflammatory conditions. These data supplement important technical and biological information on immune function of Rap2a in macrophages activated by LPS, recently reported by us (Carvalho et al., 2019) [1]. |
| format | Online Article Text |
| id | pubmed-6531833 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-65318332019-05-29 Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation Carvalho, Brener C. Oliveira, Leonardo C. Rocha, Carolina D. Fernandes, Heliana B. Oliveira, Isadora M. Leãõ, Felipe B. Valverde, Thalita M. Rego, Igor M.G. Ghosh, Sankar Silva, Aristóbolo M. Data Brief Immunology and Microbiology We present here the data to support the understanding of the implication of Rap2a GTPase in LPS-induced innate immune response and NF-κB activation. The data presented are related to molecular tools that were generated, acquired, optimized or validated to investigate Rap2a expression, activation and its effects in mammalian cells including RAW264.7 macrophages and THP-1 monocytes under inflammatory conditions. These data supplement important technical and biological information on immune function of Rap2a in macrophages activated by LPS, recently reported by us (Carvalho et al., 2019) [1]. Elsevier 2019-05-02 /pmc/articles/PMC6531833/ /pubmed/31193517 http://dx.doi.org/10.1016/j.dib.2019.103965 Text en © 2019 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Immunology and Microbiology Carvalho, Brener C. Oliveira, Leonardo C. Rocha, Carolina D. Fernandes, Heliana B. Oliveira, Isadora M. Leãõ, Felipe B. Valverde, Thalita M. Rego, Igor M.G. Ghosh, Sankar Silva, Aristóbolo M. Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation |
| title | Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation |
| title_full | Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation |
| title_fullStr | Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation |
| title_full_unstemmed | Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation |
| title_short | Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation |
| title_sort | data in support of rap2a gtpase expression, activation and effects in lps-mediated innate immune response and nf-κb activation |
| topic | Immunology and Microbiology |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531833/ https://www.ncbi.nlm.nih.gov/pubmed/31193517 http://dx.doi.org/10.1016/j.dib.2019.103965 |
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