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Adipose Lipocalin 2 overexpression protects against age-related decline in thermogenic function of adipose tissue and metabolic deterioration
OBJECTIVES: Aging increases the risk for development of adipose tissue dysfunction, insulin resistance, dyslipidemia, and liver steatosis. Lipocalin 2 (Lcn2) deficient mice are more prone to diet-induced obesity and metabolic dysfunction, indicating a protective role for Lcn2 in younger mice. In thi...
Autores principales: | Deis, Jessica A., Guo, Hong, Wu, Yingjie, Liu, Chengyu, Bernlohr, David A., Chen, Xiaoli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531839/ https://www.ncbi.nlm.nih.gov/pubmed/30928474 http://dx.doi.org/10.1016/j.molmet.2019.03.007 |
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