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Adipose Lipocalin 2 overexpression protects against age-related decline in thermogenic function of adipose tissue and metabolic deterioration

OBJECTIVES: Aging increases the risk for development of adipose tissue dysfunction, insulin resistance, dyslipidemia, and liver steatosis. Lipocalin 2 (Lcn2) deficient mice are more prone to diet-induced obesity and metabolic dysfunction, indicating a protective role for Lcn2 in younger mice. In thi...

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Detalles Bibliográficos
Autores principales: Deis, Jessica A., Guo, Hong, Wu, Yingjie, Liu, Chengyu, Bernlohr, David A., Chen, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531839/
https://www.ncbi.nlm.nih.gov/pubmed/30928474
http://dx.doi.org/10.1016/j.molmet.2019.03.007

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