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Attenuation of a Pathogenic Mycoplasma Strain by Modification of the obg Gene by Using Synthetic Biology Approaches

Mycoplasma species are responsible for several economically significant livestock diseases for which there is a need for new and improved vaccines. Most of the existing mycoplasma vaccines are attenuated strains that have been empirically obtained by serial passages or by chemical mutagenesis. The r...

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Detalles Bibliográficos
Autores principales: Lartigue, Carole, Valverde Timana, Yanina, Labroussaa, Fabien, Schieck, Elise, Liljander, Anne, Sacchini, Flavio, Posthaus, Horst, Batailler, Brigitte, Sirand-Pugnet, Pascal, Vashee, Sanjay, Jores, Joerg, Blanchard, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531878/
https://www.ncbi.nlm.nih.gov/pubmed/31118296
http://dx.doi.org/10.1128/mSphere.00030-19