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Titrating Gene Function in the Human Fungal Pathogen Candida albicans through Poly-Adenosine Tract Insertion

A recent study demonstrated that the insertion of poly-adenosine (poly-A) tracts into an open reading frame can suppress expression of the encoded protein in both prokaryotic and eukaryotic species. Furthermore, the degree of suppression is proportional to the length of the poly-A insertion, which c...

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Detalles Bibliográficos
Autores principales: Tournu, Helene, Butts, Arielle, Palmer, Glen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531883/
https://www.ncbi.nlm.nih.gov/pubmed/31118301
http://dx.doi.org/10.1128/mSphere.00192-19