Reactivity and Selectivity of Iminium Organocatalysis Improved by a Protein Host

There has been growing interest in performing organocatalysis within a supramolecular system as a means of controlling reaction reactivity and stereoselectivity. Here, a protein is used as a host for iminium catalysis. A pyrrolidine moiety is covalently linked to biotin and introduced to the protein...

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Detalles Bibliográficos
Autores principales: Nödling, Alexander R., Świderek, Katarzyna, Castillo, Raquel, Hall, Jonathan W., Angelastro, Antonio, Morrill, Louis C., Jin, Yi, Tsai, Yu‐Hsuan, Moliner, Vicent, Luk, Louis Y. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531919/
https://www.ncbi.nlm.nih.gov/pubmed/30027571
http://dx.doi.org/10.1002/anie.201806850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531919/
https://www.ncbi.nlm.nih.gov/pubmed/30027571
http://dx.doi.org/10.1002/anie.201806850

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