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Reactivity and Selectivity of Iminium Organocatalysis Improved by a Protein Host
There has been growing interest in performing organocatalysis within a supramolecular system as a means of controlling reaction reactivity and stereoselectivity. Here, a protein is used as a host for iminium catalysis. A pyrrolidine moiety is covalently linked to biotin and introduced to the protein...
Autores principales: | Nödling, Alexander R., Świderek, Katarzyna, Castillo, Raquel, Hall, Jonathan W., Angelastro, Antonio, Morrill, Louis C., Jin, Yi, Tsai, Yu‐Hsuan, Moliner, Vicent, Luk, Louis Y. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531919/ https://www.ncbi.nlm.nih.gov/pubmed/30027571 http://dx.doi.org/10.1002/anie.201806850 |
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