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Chemotherapeutic Agent Paclitaxel Mediates Priming of NLRP3 Inflammasome Activation
Paclitaxel is a chemotherapeutic drug commonly used to treat different types of cancer. In addition to its antitumor effect, paclitaxel is also known to promote Toll-like receptor (TLR) 4-dependent inflammatory responses, which may lower its chemotherapeutic efficacy. However, it remains unclear whe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532018/ https://www.ncbi.nlm.nih.gov/pubmed/31156650 http://dx.doi.org/10.3389/fimmu.2019.01108 |