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Chemotherapeutic Agent Paclitaxel Mediates Priming of NLRP3 Inflammasome Activation

Paclitaxel is a chemotherapeutic drug commonly used to treat different types of cancer. In addition to its antitumor effect, paclitaxel is also known to promote Toll-like receptor (TLR) 4-dependent inflammatory responses, which may lower its chemotherapeutic efficacy. However, it remains unclear whe...

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Detalles Bibliográficos
Autores principales: Son, Seunghwan, Shim, Do-Wan, Hwang, Inhwa, Park, Jong-Hwan, Yu, Je-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532018/
https://www.ncbi.nlm.nih.gov/pubmed/31156650
http://dx.doi.org/10.3389/fimmu.2019.01108