Trans-chalcone activity against Trichophyton rubrum relies on an interplay between signaling pathways related to cell wall integrity and fatty acid metabolism

BACKGROUND: Trichophyton rubrum is the main etiological agent of skin and nail infections worldwide. Because of its keratinolytic activity and anthropophilic nature, infection models based on the addition of protein substrates have been employed to assess transcriptional profiles and to elucidate as...

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Detalles Bibliográficos
Autores principales: Bitencourt, Tamires Aparecida, Macedo, Claudia, Franco, Matheus Eloy, Rocha, Marina Campos, Moreli, Igor Sawasaki, Cantelli, Bruna Aline Micheloto, Sanches, Pablo Rodrigo, Beleboni, Rene Oliveira, Malavazi, Iran, Passos, Geraldo Aleixo, Marins, Mozart, Fachin, Ana Lúcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532161/
https://www.ncbi.nlm.nih.gov/pubmed/31117938
http://dx.doi.org/10.1186/s12864-019-5792-0

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