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Tumor necrosis factor receptor-associated protein 1 regulates hypoxia-induced apoptosis through a mitochondria-dependent pathway mediated by cytochrome c oxidase subunit II
BACKGROUND: Tumor necrosis factor receptor-associated protein 1 (TRAP1) plays a protective effect in hypoxic cardiomyocytes, but the precise mechanisms are not well clarified. The study is aimed to identify the mechanism of TRAP1 on hypoxic damage in cardiomyocytes. METHODS: In this study, the effec...
Autores principales: | Xiang, Fei, Ma, Si-yuan, Lv, Yan-ling, Zhang, Dong-xia, Song, Hua-pei, Huang, Yue-sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532166/ https://www.ncbi.nlm.nih.gov/pubmed/31143823 http://dx.doi.org/10.1186/s41038-019-0154-3 |
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