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miR-301a promotes lung tumorigenesis by suppressing Runx3

BACKGROUND: Our previous report demonstrated that genetic ablation of miR-301a reduces Kras-driven lung tumorigenesis in mice. However, the impact of miR-301a on host anti-tumor immunity remains unexplored. Here we assessed the underlying molecular mechanisms of miR-301a in the tumor microenvironmen...

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Detalles Bibliográficos
Autores principales: Li, Xun, Zhong, Mingtian, Wang, Jiexuan, Wang, Lei, Lin, Zhanwen, Cao, Zhi, Huang, Zhujuan, Zhang, Fengxue, Li, Yong, Liu, Ming, Ma, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532219/
https://www.ncbi.nlm.nih.gov/pubmed/31122259
http://dx.doi.org/10.1186/s12943-019-1024-0

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