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Reactive oxygen species-dependent mitochondrial dynamics and autophagy confer protective effects in retinal pigment epithelial cells against sodium iodate-induced cell death
BACKGROUND: Oxidative stress is a major factor in retinal pigment epithelium (RPE) cells injury that contributes to age-related macular degeneration (AMD). NaIO3 is an oxidative toxic agent and its selective RPE cell damage makes it as a reproducible model of AMD. Although NaIO3 is an oxidative stre...
Autores principales: | Chan, Chi-Ming, Huang, Duen-Yi, Sekar, Ponarulselvam, Hsu, Shu-Hao, Lin, Wan-Wan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532221/ https://www.ncbi.nlm.nih.gov/pubmed/31118030 http://dx.doi.org/10.1186/s12929-019-0531-z |
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