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Tetrahydrocurcumin Ameliorates Diabetic Cardiomyopathy by Attenuating High Glucose-Induced Oxidative Stress and Fibrosis via Activating the SIRT1 Pathway
Hyperglycemia-induced oxidative stress and fibrosis play a crucial role in the development of diabetic cardiomyopathy (DCM). Tetrahydrocurcumin (THC), a major bioactive metabolite of natural antioxidant curcumin, is reported to exert even more effective antioxidative and superior antifibrotic proper...
Autores principales: | Li, Kaifeng, Zhai, Mengen, Jiang, Liqing, Song, Fan, Zhang, Bin, Li, Jie, Li, Hua, Li, Buying, Xia, Lin, Xu, Lu, Cao, Yu, He, Mengshan, Zhu, Hanzhao, Zhang, Liyun, Liang, Hongliang, Jin, Zhenxiao, Duan, Weixun, Wang, Siwang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532281/ https://www.ncbi.nlm.nih.gov/pubmed/31210844 http://dx.doi.org/10.1155/2019/6746907 |
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