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Comprehensive Modeling of Spinal Muscular Atrophy in Drosophila melanogaster

Spinal muscular atrophy (SMA) is a neurodegenerative disorder that affects motor neurons, primarily in young children. SMA is caused by mutations in the Survival Motor Neuron 1 (SMN1) gene. SMN functions in the assembly of spliceosomal RNPs and is well conserved in many model systems including mouse...

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Detalles Bibliográficos
Autores principales:	Spring, Ashlyn M., Raimer, Amanda C., Hamilton, Christine D., Schillinger, Michela J., Matera, A. Gregory
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532329/ https://www.ncbi.nlm.nih.gov/pubmed/31156382 http://dx.doi.org/10.3389/fnmol.2019.00113

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