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Effect of rituximab treatment on T and B cell subsets in lymph node biopsies of patients with rheumatoid arthritis

OBJECTIVES: The exact underlying mechanism of rituximab treatment in patients with RA is poorly defined and knowledge about the effect of B cell depletion on immune cells in secondary lymphoid organs is lacking. We analysed lymphoid tissue responses to rituximab in RA patients. METHODS: Fourteen RA...

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Detalles Bibliográficos
Autores principales: Ramwadhdoebe, Tamara H, van Baarsen, Lisa G M, Boumans, Maria J H, Bruijnen, Stefan T G, Safy, Mary, Berger, Ferco H, Semmelink, Johanna F, van der Laken, Conny J, Gerlag, Danielle M, Thurlings, Rogier M, Tak, Paul P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532448/
https://www.ncbi.nlm.nih.gov/pubmed/30649469
http://dx.doi.org/10.1093/rheumatology/key428