Cargando…

Risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an Indian quadragenarian with schizo-obsessive disorder

Tardive dyskinesia (TD) is a chronic, stigmatizing side effect of typical and atypical antipsychotics that is often debilitating for the patient and resistant to treatment. Obsessive–compulsive symptoms (OCS) may arise at any stage of schizophrenia ranging from prodrome to posttreatment and carry a...

Descripción completa

Detalles Bibliográficos
Autores principales: Nayak, Ajita S., Merchant, Heena H., Nachane, Hrishikesh B., Anvekar, Aditya R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532469/
https://www.ncbi.nlm.nih.gov/pubmed/31142912
http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_414_18
_version_ 1783421035064852480
author Nayak, Ajita S.
Merchant, Heena H.
Nachane, Hrishikesh B.
Anvekar, Aditya R.
author_facet Nayak, Ajita S.
Merchant, Heena H.
Nachane, Hrishikesh B.
Anvekar, Aditya R.
author_sort Nayak, Ajita S.
collection PubMed
description Tardive dyskinesia (TD) is a chronic, stigmatizing side effect of typical and atypical antipsychotics that is often debilitating for the patient and resistant to treatment. Obsessive–compulsive symptoms (OCS) may arise at any stage of schizophrenia ranging from prodrome to posttreatment and carry a poor prognosis. Management of both the conditions is a challenging and often fatiguing task for the treating physician. We report a case of schizo-obsessive disorder in an Indian quadragenarian who had developed TD with olanzapine and had failed to show improvement with clozapine and quetiapine. The patient improved dramatically with risperidone. Our findings corroborate with previous literature which has shown risperidone to be effective in treatment of TD and obsessive symptoms, possibly due to its action on the serotonergic system. The authors conclude that risperidone is an effective choice to treat TD and comorbid OCS in patients with schizophrenia.
format Online
Article
Text
id pubmed-6532469
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-65324692019-05-29 Risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an Indian quadragenarian with schizo-obsessive disorder Nayak, Ajita S. Merchant, Heena H. Nachane, Hrishikesh B. Anvekar, Aditya R. Indian J Psychiatry Case Report Tardive dyskinesia (TD) is a chronic, stigmatizing side effect of typical and atypical antipsychotics that is often debilitating for the patient and resistant to treatment. Obsessive–compulsive symptoms (OCS) may arise at any stage of schizophrenia ranging from prodrome to posttreatment and carry a poor prognosis. Management of both the conditions is a challenging and often fatiguing task for the treating physician. We report a case of schizo-obsessive disorder in an Indian quadragenarian who had developed TD with olanzapine and had failed to show improvement with clozapine and quetiapine. The patient improved dramatically with risperidone. Our findings corroborate with previous literature which has shown risperidone to be effective in treatment of TD and obsessive symptoms, possibly due to its action on the serotonergic system. The authors conclude that risperidone is an effective choice to treat TD and comorbid OCS in patients with schizophrenia. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6532469/ /pubmed/31142912 http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_414_18 Text en Copyright: © 2019 Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Nayak, Ajita S.
Merchant, Heena H.
Nachane, Hrishikesh B.
Anvekar, Aditya R.
Risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an Indian quadragenarian with schizo-obsessive disorder
title Risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an Indian quadragenarian with schizo-obsessive disorder
title_full Risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an Indian quadragenarian with schizo-obsessive disorder
title_fullStr Risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an Indian quadragenarian with schizo-obsessive disorder
title_full_unstemmed Risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an Indian quadragenarian with schizo-obsessive disorder
title_short Risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an Indian quadragenarian with schizo-obsessive disorder
title_sort risperidone as an effective choice for obsessive–compulsive symptoms and tardive dyskinesia in an indian quadragenarian with schizo-obsessive disorder
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532469/
https://www.ncbi.nlm.nih.gov/pubmed/31142912
http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_414_18
work_keys_str_mv AT nayakajitas risperidoneasaneffectivechoiceforobsessivecompulsivesymptomsandtardivedyskinesiainanindianquadragenarianwithschizoobsessivedisorder
AT merchantheenah risperidoneasaneffectivechoiceforobsessivecompulsivesymptomsandtardivedyskinesiainanindianquadragenarianwithschizoobsessivedisorder
AT nachanehrishikeshb risperidoneasaneffectivechoiceforobsessivecompulsivesymptomsandtardivedyskinesiainanindianquadragenarianwithschizoobsessivedisorder
AT anvekaradityar risperidoneasaneffectivechoiceforobsessivecompulsivesymptomsandtardivedyskinesiainanindianquadragenarianwithschizoobsessivedisorder