Impairment and Restoration of Homeostatic Plasticity in Cultured Cortical Neurons From a Mouse Model of Huntington Disease

Huntington disease (HD) is an inherited neurodegenerative disorder caused by a mutation in the huntingtin gene. The onset of symptoms is preceded by synaptic dysfunction. Homeostatic synaptic plasticity (HSP) refers to processes that maintain the stability of networks of neurons, thought to be requi...

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Detalles Bibliográficos
Autores principales: Smith-Dijak, Amy I., Nassrallah, Wissam B., Zhang, Lily Y. J., Geva, Michal, Hayden, Michael R., Raymond, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532531/
https://www.ncbi.nlm.nih.gov/pubmed/31156395
http://dx.doi.org/10.3389/fncel.2019.00209

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