Cargando…
Enantiospecific Synthesis, Chiral Separation, and Biological Activity of Four Indazole-3-Carboxamide-Type Synthetic Cannabinoid Receptor Agonists and Their Detection in Seized Drug Samples
Synthetic cannabinoid receptor agonists (SCRAs) have been the largest group of illicit psychoactive substances reported to international monitoring and early warning systems for many years. Carboxamide-type SCRAs are amongst the most prevalent and potent. Enantiospecific synthesis and characterizati...
Autores principales: | Antonides, Lysbeth H., Cannaert, Annelies, Norman, Caitlyn, Vives, Loelia, Harrison, Aidan, Costello, Andrew, Nic Daeid, Niamh, Stove, Christophe P., Sutcliffe, Oliver B., McKenzie, Craig |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532652/ https://www.ncbi.nlm.nih.gov/pubmed/31157203 http://dx.doi.org/10.3389/fchem.2019.00321 |
Ejemplares similares
-
A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on the Illicit Drug Market
por: Brandon, Andrew M., et al.
Publicado: (2021) -
Activation of μ‐opioid receptors by MT‐45 (1‐cyclohexyl‐4‐(1,2‐diphenylethyl)piperazine) and its fluorinated derivatives
por: Baptista‐Hon, Daniel T., et al.
Publicado: (2020) -
Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users
por: McKenzie, Craig, et al.
Publicado: (2018) -
Inhibitory Effect of AB-PINACA, Indazole Carboxamide Synthetic Cannabinoid, on Human Major Drug-Metabolizing Enzymes and Transporters
por: Park, Eun Jeong, et al.
Publicado: (2020) -
Enantiospecific Pharmacogenomics of Fluvastatin
por: Hirvensalo, Päivi, et al.
Publicado: (2019)