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Genetic Variation in CRHR1 is Associated with Short-Term Respiratory Response to Corticosteroids in Preterm Infants at risk for Bronchopulmonary Dysplasia

BACKGROUND: Bronchopulmonary Dysplasia (BPD) is an orphan disease and advances in prevention and treatment are lacking. Clinical efficacy of systemic corticosteroid therapy to reduce the severity of lung disease and BPD is highly variable. Our objective was to assess whether candidate SNPs in cortic...

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Detalles Bibliográficos
Autores principales: Lewis, Tamorah, Truog, William, Norberg, Mike, Ballard, Philip L., Torgerson, Dara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532775/
https://www.ncbi.nlm.nih.gov/pubmed/30467342
http://dx.doi.org/10.1038/s41390-018-0235-1