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Dynamic modelling of an ACADS genotype in fatty acid oxidation – Application of cellular models for the analysis of common genetic variants

BACKGROUND: Genome-wide association studies of common diseases or metabolite quantitative traits often identify common variants of small effect size, which may contribute to phenotypes by modulation of gene expression. Thus, there is growing demand for cellular models enabling to assess the impact o...

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Detalles Bibliográficos
Autores principales:	Matejka, Kerstin, Stückler, Ferdinand, Salomon, Michael, Ensenauer, Regina, Reischl, Eva, Hoerburger, Lena, Grallert, Harald, Kastenmüller, Gabi, Peters, Annette, Daniel, Hannelore, Krumsiek, Jan, Theis, Fabian J., Hauner, Hans, Laumen, Helmut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532850/ https://www.ncbi.nlm.nih.gov/pubmed/31120904 http://dx.doi.org/10.1371/journal.pone.0216110

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