CD4+ T cell cytokine responses to the DAR-901 booster vaccine in BCG-primed adults: A randomized, placebo-controlled trial

BACKGROUND: DAR-901 is an inactivated whole cell tuberculosis booster vaccine, prepared using a new scalable, broth-grown method from the master cell bank of SRL172, a vaccine previously shown to prevent tuberculosis. This study examined whether DAR-901 (a) induces CD4+ T cell cytokine profiles prev...

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Detalles Bibliográficos
Autores principales: Masonou, Tereza, Hokey, David A., Lahey, Timothy, Halliday, Alice, Berrocal-Almanza, Luis C., Wieland-Alter, Wendy F., Arbeit, Robert D., Lalvani, Ajit, von Reyn, C. Fordham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532882/
https://www.ncbi.nlm.nih.gov/pubmed/31120957
http://dx.doi.org/10.1371/journal.pone.0217091

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