Cargando…

Rapid antigen diversification through mitotic recombination in the human malaria parasite Plasmodium falciparum

Malaria parasites possess the remarkable ability to maintain chronic infections that fail to elicit a protective immune response, characteristics that have stymied vaccine development and cause people living in endemic regions to remain at risk of malaria despite previous exposure to the disease. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xu, Alexander, Noah, Leonardi, Irina, Mason, Christopher, Kirkman, Laura A., Deitsch, Kirk W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532940/ https://www.ncbi.nlm.nih.gov/pubmed/31083650 http://dx.doi.org/10.1371/journal.pbio.3000271

Ejemplares similares

Chromosome End Repair and Genome Stability in Plasmodium falciparum
por: Calhoun, Susannah F., et al.
Publicado: (2017)

Uncovering the role of Rad51 in homologous recombination-mediated antigenic diversification in the human malaria parasite Plasmodium falciparum
por: Vydyam, Pratap, et al.
Publicado: (2023)

Horizontal gene transfer of epigenetic machinery and evolution of parasitism in the malaria parasite Plasmodium falciparum and other apicomplexans
por: Kishore, Sandeep P, et al.
Publicado: (2013)

Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity
por: Kirkman, Laura A., et al.
Publicado: (2014)

The human malaria parasite Plasmodium falciparum can sense environmental changes and respond by antigenic switching
por: Schneider, Victoria M., et al.
Publicado: (2023)

Gene Silencing and Antigenic Variation in Malaria Parasites
por: Deitsch, Kirk W.
Publicado: (2001)

A regulatable transgene expression system for cultured Plasmodium falciparum parasites
por: Epp, Christian, et al.
Publicado: (2008)

Telomere length dynamics in response to DNA damage in malaria parasites
por: Reed, Jake, et al.
Publicado: (2021)

A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum
por: Ukaegbu, Uchechi E., et al.
Publicado: (2015)

Mutually Exclusive Expression of Virulence Genes by Malaria Parasites Is Regulated Independently of Antigen Production
por: Dzikowski, Ron, et al.
Publicado: (2006)

Polyamine uptake in the malaria parasite, Plasmodium falciparum, is dependent on the parasite's membrane potential
por: Niemand, J, et al.
Publicado: (2010)

Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families
por: Bopp, Selina E. R., et al.
Publicado: (2013)

Polyamine uptake in the malaria parasite, Plasmodium falciparum, is dependent on the parasite's membrane potential
por: Niemand, J, et al.
Publicado: (2010)

Evolution of transcriptional control of antigenic variation and virulence in human and ape malaria parasites
por: Gross, Mackensie R., et al.
Publicado: (2021)

Self-targeting blocks malaria parasite invasion
por: Deitsch, Kirk W.
Publicado: (2015)

DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families
por: Sander, Adam F., et al.
Publicado: (2014)

Plasmodium falciparum malaria cases detected for prompt treatment by rapid diagnostic tests in the Ho Teaching Hospital of the Volta Region of Ghana
por: Dinko, Bismarck, et al.
Publicado: (2018)

Characterization of Plasmodium falciparum Adenylyl Cyclase-β and Its Role in Erythrocytic Stage Parasites
por: Salazar, Eric, et al.
Publicado: (2012)

Evolution of Host Specificity by Malaria Parasites through Altered Mechanisms Controlling Genome Maintenance
por: Siao, Michelle C., et al.
Publicado: (2020)

Transcriptional variation in the malaria parasite Plasmodium falciparum
por: Rovira-Graells, Núria, et al.
Publicado: (2012)

A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites
por: Zhang, Xu, et al.
Publicado: (2022)

The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum
por: Martin, Rowena E, et al.
Publicado: (2005)

The Link between Plasmodium falciparum Malaria and Endemic Burkitt’s Lymphoma—New Insight into a 50-Year-Old Enigma
por: Thorley-Lawson, David, et al.
Publicado: (2016)

Plasmodium falciparum parasites causing cerebral malaria share variant surface antigens, but are they specific?
por: Kheliouen, Nabila, et al.
Publicado: (2010)

An antigenic diversification threshold for falciparum malaria transmission at high endemicity
por: He, Qixin, et al.
Publicado: (2021)

Diagnostic Performance of Three Rapid Diagnostic Test Kits for Malaria Parasite Plasmodium falciparum
por: Park, Seo Hye, et al.
Publicado: (2020)

Circumsporozoite proteins of human malaria parasites Plasmodium falciparum and Plasmodium vivax
Publicado: (1982)

The protein-phosphatome of the human malaria parasite Plasmodium falciparum
por: Wilkes, Jonathan M, et al.
Publicado: (2008)

Origin of the human malaria parasite Plasmodium falciparum in gorillas
por: Liu, Weimin, et al.
Publicado: (2010)

Alternative Protein Secretion in the Malaria Parasite Plasmodium falciparum
por: Thavayogarajah, Thuvaraka, et al.
Publicado: (2015)

Polymorphism of a high molecular weight schizont antigen of the human malaria parasite Plasmodium falciparum
Publicado: (1985)

Correction: An antigenic diversification threshold for falciparum malaria transmission at high endemicity
Publicado: (2021)

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum
por: Wilson, Danny W, et al.
Publicado: (2015)

Identifying functional groups among the diverse, recombining antigenic var genes of the malaria parasite Plasmodium falciparum from a local community in Ghana
por: Rorick, Mary M., et al.
Publicado: (2018)

Invasion of mouse erythrocytes by the human malaria parasite, Plasmodium falciparum
Publicado: (1987)

Protease-associated cellular networks in malaria parasite Plasmodium falciparum
por: Lilburn, Timothy G, et al.
Publicado: (2011)

Targeting NAD(+) Metabolism in the Human Malaria Parasite Plasmodium falciparum
por: O'Hara, Jessica K., et al.
Publicado: (2014)

The multifunctional autophagy pathway in the human malaria parasite, Plasmodium falciparum
por: Cervantes, Serena, et al.
Publicado: (2014)

CRISPR-mediated genome editing of Plasmodium falciparum malaria parasites
por: Lee, Marcus CS, et al.
Publicado: (2014)

Characterization of the accessible genome in the human malaria parasite Plasmodium falciparum
por: Ruiz, José Luis, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rmkt9mup0ovub4a7shh3dgsa9s