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CD45Rb-low effector T cells require IL-4 to induce IL-10 in FoxP3 Tregs and to protect mice from inflammation
CD4(+) effector/memory T cells (Tem) represent a leading edge of the adaptive immune system responsible for protecting the body from infection, cancer, and other damaging processes. However, a subset of Tem cells with low expression of CD45Rb (Rb(Lo)Tem) has been shown to suppress inflammation despi...
Autores principales: | Jones, Mark B., Alvarez, Carlos A., Johnson, Jenny L., Zhou, Julie Y., Morris, Nathan, Cobb, Brian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533033/ https://www.ncbi.nlm.nih.gov/pubmed/31120919 http://dx.doi.org/10.1371/journal.pone.0216893 |
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