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Voluntary wheel running activates Akt/AMPK/eNOS signaling cascades without improving profound endothelial dysfunction in mice deficient in α-galactosidase A

Fabry disease is caused by loss of activity of the lysosomal hydrolase α-galactosidase A (GLA). Premature life-threatening complications in Fabry patients arise from cardiovascular disease, including stroke and myocardial infarction. Exercise training has been shown to improve endothelial dysfunctio...

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Detalles Bibliográficos
Autores principales:	Kang, Justin J., Treadwell, Taylour A., Bodary, Peter F., Shayman, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533039/ https://www.ncbi.nlm.nih.gov/pubmed/31120949 http://dx.doi.org/10.1371/journal.pone.0217214

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