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Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

Chromosomal DNA elements are organized into spatial domains within the eukaryotic nucleus. Sites undergoing DNA replication, high-level transcription, and repair of double-strand breaks coalesce into foci, although the significance and mechanisms giving rise to these dynamic structures are poorly un...

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Detalles Bibliográficos
Autores principales:	Zhang, Haiyang, Petrie, Meghan V, He, Yiwei, Peace, Jared M, Chiolo, Irene E, Aparicio, Oscar M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533057/ https://www.ncbi.nlm.nih.gov/pubmed/31084713 http://dx.doi.org/10.7554/eLife.45512

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