Synthesis, characterization, and POM-protein interactions of a Fe-substituted Krebs-type Sandwich-tungstoantimonate

ABSTRACT: The novel iron-substituted Krebs-type polyoxotungstate (C(12)N(4)H(11))(4)Na(2)H(5)[(Fe(H(2)O)(3))(2)((FeO(2))(0.5)(WO(2))(0.5))(2)(β-SbW(9)O(33))(2)] (Fe-1) has been synthesized using ortho-phenylenediamine (opda) as a precursor for the in situ formation of the counter cation 2,3-diaminophenazinium (C(12)N(4)H(11))(+) (2,3-DAP). Fe-1 has been thoroughly characterized in the solid state by single-crystal X-ray diffraction (SXRD), powder X-ray diffraction (PXRD), IR spectroscopy, and elemental analysis as well as in solution by UV–Vis spectroscopy. The crystal structure of Fe-1 reveals π–π-interactions between the aromatic systems of the unconventional 2,3-DAP counter cation. POM-protein interaction studies using SDS-PAGE revealed a non-proteolytic behavior of Fe-1 towards Human Serum Albumin (HSA) as a model protein. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00706-019-2381-5) contains supplementary material, which is available to authorized users.