Nicotinamide phosphoribosyltransferase is a molecular target of potent anticancer agents identified from phenotype-based drug screening

Phenotypic screening in drug discovery has been revived with the expectation of providing promising lead compounds and drug targets and improving the success rate of drug approval. However, target identification remains a major bottleneck in phenotype-based drug discovery. We identified the lead com...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Daisuke, Imaizumi, Takamichi, Yagi, Kaori, Matsumoto, Yuichi, Nakashima, Takayuki, Hirose, Akiyo, Kashima, Naomi, Nosaka, Yukino, Hamada, Tomoko, Okawa, Katsuya, Nishiya, Yoichi, Kubo, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533267/
https://www.ncbi.nlm.nih.gov/pubmed/31123329
http://dx.doi.org/10.1038/s41598-019-43994-x

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