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BRAF inhibition sensitizes melanoma cells to α-amanitin via decreased RNA polymerase II assembly
Despite the great success of small molecule inhibitors in the treatment of patients with BRAF(V600E) mutated melanoma, the response to these drugs remains transient and patients eventually relapse within a few months, highlighting the need to develop novel combination therapies based on the understa...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533289/ https://www.ncbi.nlm.nih.gov/pubmed/31123282 http://dx.doi.org/10.1038/s41598-019-44112-7 |