PI3‐kinase/Akt pathway‐regulated membrane transportation of acid‐sensing ion channel 1a/Calcium ion influx/endoplasmic reticulum stress activation on PDGF‐induced HSC Activation

Acid‐sensing ion channel 1a (ASIC1a) allows Na(+) and Ca(2+) flow into cells. It is expressed during inflammation, in tumour and ischaemic tissue, in the central nervous system and non‐neuronal injury environments. Endoplasmic reticulum stress (ERS) is caused by the accumulation of misfolded protein...

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Detalles Bibliográficos
Autores principales: Zuo, Longquan, Zhu, Yueqin, Hu, Lili, Liu, Yanyi, Wang, Yinghong, Hu, Yamin, Wang, Huan, Pan, Xuesheng, Li, Kuayue, Du, Na, Huang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533492/
https://www.ncbi.nlm.nih.gov/pubmed/30938088
http://dx.doi.org/10.1111/jcmm.14275

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