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Non-sterile Submerged Fermentation of Fibrinolytic Enzyme by Marine Bacillus subtilis Harboring Antibacterial Activity With Starvation Strategy
Microbial fibrinolytic enzyme is a promising candidate for thrombolytic therapy. Non-sterile production of fibrinolytic enzyme by marine Bacillus subtilis D21-8 under submerged fermentation was realized at a mild temperature of 34°C, using a unique combination of starvation strategy and self-product...
Autores principales: | Pan, Shihan, Chen, Guiguang, Wu, Rui, Cao, Xiaoyan, Liang, Zhiqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533532/ https://www.ncbi.nlm.nih.gov/pubmed/31156576 http://dx.doi.org/10.3389/fmicb.2019.01025 |
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