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Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats

Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and has been shown to display vasoprotective effects in chronic ischemic stroke. The purpose of this study was to evaluate the therapeutic effect of DCA on vascular dementia (VD) and endothelial progenitor cell...

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Detalles Bibliográficos
Autores principales:	Zhao, Hui, Mao, Junqin, Yuan, Yuan, Feng, Jingjing, Cheng, Hao, Fan, Guorong, Zhang, Yuefan, Li, Tiejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533549/ https://www.ncbi.nlm.nih.gov/pubmed/31156438 http://dx.doi.org/10.3389/fphar.2019.00523

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