Cargando…

Analysis of Motor Function in the Tg4-42 Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder and the most common form of dementia. Hallmarks of AD are memory impairments and cognitive deficits, but non-cognitive impairments, especially motor dysfunctions are also associated with the disease and may even precede classic clinical sympto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wagner, Jannek M., Sichler, Marius E., Schleicher, Eva M., Franke, Timon N., Irwin, Caroline, Löw, Maximilian Johannes, Beindorff, Nicola, Bouter, Caroline, Bayer, Thomas A., Bouter, Yvonne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533559/ https://www.ncbi.nlm.nih.gov/pubmed/31156407 http://dx.doi.org/10.3389/fnbeh.2019.00107

Ejemplares similares

(18)F-FDG-PET Detects Drastic Changes in Brain Metabolism in the Tg4–42 Model of Alzheimer’s Disease
por: Bouter, Caroline, et al.
Publicado: (2019)

Reduced Acoustic Startle Response and Prepulse Inhibition in the Tg4-42 Model of Alzheimer’s Disease
por: Sichler, Marius E., et al.
Publicado: (2019)

Quantitative Brain Positron Emission Tomography in Female 5XFAD Alzheimer Mice: Pathological Features and Sex-Specific Alterations
por: Bouter, Caroline, et al.
Publicado: (2021)

In vivo Imaging With (18)F-FDG- and (18)F-Florbetaben-PET/MRI Detects Pathological Changes in the Brain of the Commonly Used 5XFAD Mouse Model of Alzheimer's Disease
por: Franke, Timon N., et al.
Publicado: (2020)

Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits
por: Curdt, Nadine, et al.
Publicado: (2022)

Prolonged Cannabidiol Treatment Lacks on Detrimental Effects on Memory, Motor Performance and Anxiety in C57BL/6J Mice
por: Schleicher, Eva M., et al.
Publicado: (2019)

(18)F-FDG-PET in Mouse Models of Alzheimer's Disease
por: Bouter, Caroline, et al.
Publicado: (2019)

miRNA Alterations Elicit Pathways Involved in Memory Decline and Synaptic Function in the Hippocampus of Aged Tg4-42 Mice
por: Bouter, Yvonne, et al.
Publicado: (2020)

Synaptic Alterations in Mouse Models for Alzheimer Disease—A Special Focus on N-Truncated Abeta 4-42
por: Dietrich, Katharina, et al.
Publicado: (2018)

Ablation of the Presynaptic Protein Mover Impairs Learning Performance and Decreases Anxiety Behavior in Mice
por: Schleicher, Eva Maria, et al.
Publicado: (2022)

Chronic exposure to a synthetic cannabinoid alters cerebral brain metabolism and causes long-lasting behavioral deficits in adult mice
por: Bouter, Caroline, et al.
Publicado: (2023)

Synergistic Effect on Neurodegeneration by N-Truncated Aβ(4−42) and Pyroglutamate Aβ(3−42) in a Mouse Model of Alzheimer's Disease
por: Lopez-Noguerola, Jose S., et al.
Publicado: (2018)

Selective Serotonin Reuptake Inhibitor-Treatment Does Not Show Beneficial Effects on Cognition or Amyloid Burden in Cognitively Impaired and Cognitively Normal Subjects
por: Bouter, Yvonne, et al.
Publicado: (2022)

Abundance of Aβ(5-x) like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer’s disease
por: Guzmán, Erika Avendaño, et al.
Publicado: (2014)

Metabolic, Phenotypic, and Neuropathological Characterization of the Tg4-42 Mouse Model for Alzheimer’s Disease
por: Hinteregger, Barbara, et al.
Publicado: (2021)

A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease
por: Shahpasand-Kroner, Hedieh, et al.
Publicado: (2018)

Donanemab detects a minor fraction of amyloid-β plaques in post-mortem brain tissue of patients with Alzheimer’s disease and Down syndrome
por: Bouter, Yvonne, et al.
Publicado: (2022)

Reproducibility of Alzheimer’s Disease Cerebrospinal Fluid-Biomarker Measurements under Clinical Routine Conditions
por: Vogelgsang, Jonathan, et al.
Publicado: (2018)

Transgene integration causes RARB downregulation in homozygous Tg4–42 mice
por: Hinteregger, Barbara, et al.
Publicado: (2020)

N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits
por: Bouter, Yvonne, et al.
Publicado: (2013)

(99m)Tc-Besilesomab-SPECT/CT in Infectious Endocarditis: Upgrade of a Forgotten Method?
por: Bouter, Caroline, et al.
Publicado: (2019)

Case Report: Two Cases of Subacute Thyroiditis Following SARS-CoV-2 Vaccination
por: Bornemann, Catherine, et al.
Publicado: (2021)

Search Strategy Analysis of 5xFAD Alzheimer Mice in the Morris Water Maze Reveals Sex- and Age-Specific Spatial Navigation Deficits
por: Sánchez, Carolina Quintanilla, et al.
Publicado: (2023)

Physical Activity Ameliorates Impaired Hippocampal Neurogenesis in the Tg4-42 Mouse Model of Alzheimer’s Disease
por: Gerberding, Anna-Lina, et al.
Publicado: (2019)

What Research Institutions Can Do to Foster Research Integrity
por: Bouter, Lex
Publicado: (2020)

Deciphering the Molecular Profile of Plaques, Memory Decline and Neuron Loss in Two Mouse Models for Alzheimer’s Disease by Deep Sequencing
por: Bouter, Yvonne, et al.
Publicado: (2014)

Protective immunity induced by DNA vaccine containing TgGRA35, TgGRA42, and TgGRA43 against Toxoplasma gondii infection in Kunming mice
por: Shi, Youbo, et al.
Publicado: (2023)

Case Report: The Role of Neuropsychological Assessment and Imaging Biomarkers in the Early Diagnosis of Lewy Body Dementia in a Patient With Major Depression and Prolonged Alcohol and Benzodiazepine Dependence
por: Bouter, Caroline, et al.
Publicado: (2020)

Assessing Nigrostriatal Dopaminergic Pathways via 123I-FP-CIT SPECT in Dementia With Lewy Bodies in a Psychiatric Patient Cohort
por: Hansen, Niels, et al.
Publicado: (2021)

Delirium-Onset of Prodromal Dementia With Lewy Bodies—Putative Brainstem-Related Pathomechanism and Clinical Relevance
por: Hansen, Niels, et al.
Publicado: (2022)

Motor deficits are independent of axonopathy in an Alzheimer's disease mouse model of TgCRND8 mice
por: Yuan, Qiuju, et al.
Publicado: (2017)

Invited Commentary on “Investigating the Reliability and Factor Structure of Kalichman’s ‘Survey 2: Research Misconduct’ Questionnaire”
por: Bouter, Lex M.
Publicado: (2017)

Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X
por: Antonios, Gregory, et al.
Publicado: (2015)

Case Report: Semantic Variant of Primary Progressive Aphasia Associated With Anti-Glial Fibrillary Acid Protein Autoantibodies
por: Hansen, Niels, et al.
Publicado: (2022)

Precautionary effects of Red Liriope platyphylla on NGF secretion and Aβ42 deposition under the preclinical stage of Alzheimer's disease in Tg2576 mice
por: Choi, Sun-Il, et al.
Publicado: (2013)

Effects on the Hypothalamo-Pituitary Axis in Patients with CNS or Head and Neck Tumors following Radiotherapy
por: Bouter, Jordan, et al.
Publicado: (2023)

Case report: Mixed dementia associated with autoantibodies targeting the vesicular glutamate transporter 2
por: Hansen, Niels, et al.
Publicado: (2023)

New Insights into Potential Biomarkers in Patients with Mild Cognitive Impairment Occurring in the Prodromal Stage of Dementia with Lewy Bodies
por: Hansen, Niels, et al.
Publicado: (2023)

Incorporating equity, diversity, and inclusiveness into the Hong Kong Principles
por: Moher, David, et al.
Publicado: (2021)

Annexins and Membrane Repair Dysfunctions in Muscular Dystrophies
por: Croissant, Coralie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ogau85h00t1b03kkkdaav7ia83