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Elucidation of the Differences in Cinobufotalin’s Pharmacokinetics Between Normal and Diethylnitrosamine-Injured Rats: The Role of P-Glycoprotein

Cinobufotalin is one of the major anti-tumor components isolated from toad venom and has been used in the clinical therapy of hepatocellular carcinoma (HCC), known as Cinobufacini injection. However, the pharmacokinetic (PK) behaviors of cinobufotalin in vivo with HCC are still unknown. Hence, we ha...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaojing, Liu, Tong, Zhang, Yidan, Liu, Fanye, Li, Haiying, Fang, Dong, Wang, Chaojie, Sun, Hua, Xie, Songqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533572/ https://www.ncbi.nlm.nih.gov/pubmed/31156437 http://dx.doi.org/10.3389/fphar.2019.00521

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