What Your Crystal Structure Will Not Tell You about Enzyme Function

[Image: see text] Enzyme function requires that enzyme structures be dynamic. Substrate binding, product release, and transition state stabilization typically involve different enzyme conformers. Furthermore, in multistep enzyme-catalyzed reactions, more than one enzyme conformation may be important...

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Detalles Bibliográficos
Autores principales: Pochapsky, Thomas C., Pochapsky, Susan Sondej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533606/
https://www.ncbi.nlm.nih.gov/pubmed/31034199
http://dx.doi.org/10.1021/acs.accounts.9b00066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533606/
https://www.ncbi.nlm.nih.gov/pubmed/31034199
http://dx.doi.org/10.1021/acs.accounts.9b00066

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