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What Your Crystal Structure Will Not Tell You about Enzyme Function
[Image: see text] Enzyme function requires that enzyme structures be dynamic. Substrate binding, product release, and transition state stabilization typically involve different enzyme conformers. Furthermore, in multistep enzyme-catalyzed reactions, more than one enzyme conformation may be important...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533606/ https://www.ncbi.nlm.nih.gov/pubmed/31034199 http://dx.doi.org/10.1021/acs.accounts.9b00066 |