Exploiting orthology and de novo transcriptome assembly to refine target sequence information

BACKGROUND: The ability to generate recombinant drug target proteins is important for drug discovery research as it facilitates the investigation of drug-target-interactions in vitro. To accomplish this, the target’s exact protein sequence is required. Public databases, such as Ensembl, UniProt and...

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Detalles Bibliográficos
Autores principales: Söllner, Julia F., Leparc, Germán, Zwick, Matthias, Schönberger, Tanja, Hildebrandt, Tobias, Nieselt, Kay, Simon, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533699/
https://www.ncbi.nlm.nih.gov/pubmed/31122257
http://dx.doi.org/10.1186/s12920-019-0524-5

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