Cargando…

High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer

BACKGROUND: Following curative-intent neoadjuvant therapy in locally advanced rectal cancer, metastatic progression is still dominant. We investigated if patients’ circulating 25-hydroxyvitamin D [25(OH)D] levels were associated with outcome. METHODS: Serum 25(OH)D concentration was assessed by liqu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abrahamsson, Hanna, Porojnicu, Alina C., Lindstrøm, Jonas C., Dueland, Svein, Flatmark, Kjersti, Hole, Knut H., Seierstad, Therese, Moan, Johan, Redalen, Kathrine Røe, Meltzer, Sebastian, Ree, Anne Hansen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533753/ https://www.ncbi.nlm.nih.gov/pubmed/31122213 http://dx.doi.org/10.1186/s12885-019-5724-z

Ejemplares similares

Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer
por: Bains, Simer J., et al.
Publicado: (2019)

Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer
por: Kalanxhi, Erta, et al.
Publicado: (2018)

Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer
por: Hektoen, Helga Helseth, et al.
Publicado: (2015)

Systemic release of osteoprotegerin during oxaliplatin-containing induction chemotherapy and favorable systemic outcome of sequential radiotherapy in rectal cancer
por: Meltzer, Sebastian, et al.
Publicado: (2016)

Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer()()
por: Bousquet, Paula A., et al.
Publicado: (2018)

Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer
por: Meltzer, Sebastian, et al.
Publicado: (2019)

Sex-related differences in primary metastatic site in rectal cancer; associated with hemodynamic factors?
por: Meltzer, Sebastian, et al.
Publicado: (2019)

Corrigendum to “Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer” [Transl Oncol 12 (8) (2019) 1038–1044]
por: Meltzer, Sebastian, et al.
Publicado: (2019)

The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
por: Meltzer, Sebastian, et al.
Publicado: (2021)

Circulating proteins in response to combined-modality therapy in rectal cancer identified by antibody array screening
por: Kalanxhi, Erta, et al.
Publicado: (2016)

Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning (1)H magnetic resonance spectroscopy
por: Seierstad, Therese, et al.
Publicado: (2008)

Biomarkers of Treatment Toxicity in Combined-Modality Cancer Therapies with Radiation and Systemic Drugs: Study Design, Multiplex Methods, Molecular Networks
por: Ree, Anne Hansen, et al.
Publicado: (2014)

Sex disparities in vitamin D status and the impact on systemic inflammation and survival in rectal cancer
por: Abrahamsson, Hanna, et al.
Publicado: (2021)

Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy
por: Kalanxhi, Erta, et al.
Publicado: (2017)

Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy
por: Bratland, Åse, et al.
Publicado: (2011)

An experimental strategy unveiling exosomal microRNAs 486-5p, 181a-5p and 30d-5p from hypoxic tumour cells as circulating indicators of high-risk rectal cancer
por: Bjørnetrø, Tonje, et al.
Publicado: (2019)

Biomarkers of Histone Deacetylase Inhibitor Activity in a Phase 1 Combined-Modality Study with Radiotherapy
por: Ree, Anne Hansen, et al.
Publicado: (2014)

Tumor Phosphatidylinositol-3-Kinase Signaling and Development of Metastatic Disease in Locally Advanced Rectal Cancer
por: Ree, Anne Hansen, et al.
Publicado: (2012)

Energy Metabolism Is Altered in Radioresistant Rectal Cancer
por: Buckley, Croí E., et al.
Publicado: (2023)

Season of diagnosis is a prognostic factor in Hodgkin's lymphoma: a possible role of sun-induced vitamin D
por: Porojnicu, A C, et al.
Publicado: (2005)

The mitochondrial DNA constitution shaping T-cell immunity in patients with rectal cancer at high risk of metastatic progression
por: Bousquet, P. A., et al.
Publicado: (2021)

Fibromatosis in vertical rectus abdominis myocutaneous flap imitating tumor recurrence after surgery for locally advanced rectal cancer: case report
por: Goscinski, Mariusz Adam, et al.
Publicado: (2016)

Early prediction of response to radiotherapy and androgen-deprivation therapy in prostate cancer by repeated functional MRI: a preclinical study
por: Røe, Kathrine, et al.
Publicado: (2011)

Monoparametric high-resolution diffusion weighted MRI as a possible first step in an MRI-directed diagnostic pathway for men with suspicion of prostate cancer
por: Reijnen, Jeroen Sebastiaan, et al.
Publicado: (2023)

Comparison of Intravoxel incoherent motion imaging and multiecho dynamic contrast‐based MRI in rectal cancer
por: Bakke, Kine Mari, et al.
Publicado: (2019)

Imaging the tumour microenvironment in rectal cancer: Decline in tumour blood flow during radiotherapy predicts good outcome
por: Bakke, Kine Mari, et al.
Publicado: (2023)

Tumor kinase activity in locally advanced rectal cancer: angiogenic signaling and early systemic dissemination
por: Saelen, Marie Grøn, et al.
Publicado: (2011)

ASO Author Reflections: Navigation-Assisted Surgery for Locally Advanced and Recurrent Rectal Cancer: The NAVI-LARRC Trial
por: Solbakken, Arne M., et al.
Publicado: (2023)

MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
por: Mo, Torgeir, et al.
Publicado: (2023)

Future directions on the merge of quantitative imaging and artificial intelligence in radiation oncology
por: Redalen, Kathrine Røe, et al.
Publicado: (2020)

Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells
por: Risberg, Karianne, et al.
Publicado: (2016)

Routine pelvic MRI using phased-array coil for detection of extraprostatic tumour extension: accuracy and clinical significance
por: Hole, Knut Håkon, et al.
Publicado: (2012)

Comparison of time curves from dynamic (18)F-fluciclovine positron emission tomography and dynamic contrast-enhanced magnetic resonance imaging for primary prostate carcinomas
por: Tulipan, Andreas Julius, et al.
Publicado: (2018)

Total Neoadjuvant Treatment of Locally Advanced Rectal Cancer with High Risk Factors in Slovenia
por: Tuta, Mojca, et al.
Publicado: (2019)

Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
por: Jonsson, Marte, et al.
Publicado: (2016)

Development of an automated production process of [(64)Cu][Cu (ATSM)] for positron emission tomography imaging and theranostic applications
por: Liu, Tengzhi, et al.
Publicado: (2022)

Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
por: Thorgersen, Ebbe Billmann, et al.
Publicado: (2021)

Semi-automatic tumor segmentation of rectal cancer based on functional magnetic resonance imaging
por: Knuth, Franziska, et al.
Publicado: (2022)

A Prospective Study of High Dose-Rate Brachytherapy or Stereotactic Body Radiotherapy of Intra-Prostatic Recurrence: Toxicity and Long Term Clinical Outcome
por: Ryg, Una, et al.
Publicado: (2022)

Multimodal functional imaging for early response assessment in GIST patients treated with imatinib
por: Revheim, Mona-Elisabeth, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fbh6ij0uo5rjtvke5avdv6iuu6