Cargando…

Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha

Background: Thyroid hormones act in bone and cartilage via thyroid hormone receptor alpha (TRα). In the absence of triiodothyronine (T3), TRα interacts with co-repressors, including nuclear receptor co-repressor-1 (NCoR1), which recruit histone deacetylases (HDACs) and mediate transcriptional repres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Freudenthal, Bernard, Shetty, Samiksha, Butterfield, Natalie C., Logan, John G., Han, Cho Rong, Zhu, Xuguang, Astapova, Inna, Hollenberg, Anthony N., Cheng, Sheue-Yann, Bassett, J.H. Duncan, Williams, Graham R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2019
Materias:	Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533791/ https://www.ncbi.nlm.nih.gov/pubmed/30760120 http://dx.doi.org/10.1089/thy.2018.0399

Ejemplares similares

Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi
por: Di Cicco, Emery, et al.
Publicado: (2021)

Contrasting Phenotypes in Resistance to Thyroid Hormone Alpha Correlate with Divergent Properties of Thyroid Hormone Receptor α1 Mutant Proteins
por: Moran, Carla, et al.
Publicado: (2017)

Transcriptome Network Analysis Reveals Aging-Related Mitochondrial and Proteasomal Dysfunction and Immune Activation in Human Thyroid
por: Cho, Byuri Angela, et al.
Publicado: (2018)

Dimerization of the Sodium/Iodide Symporter
por: Thompson, Rebecca J., et al.
Publicado: (2019)

Thyroid Hormone Transporters in a Human Placental Cell Model
por: Chen, Zhongli, et al.
Publicado: (2022)

Basolateral Sorting of the Sodium/Iodide Symporter Is Mediated by Adaptor Protein 1 Clathrin Adaptor Complexes
por: Koumarianou, Petrina, et al.
Publicado: (2022)

Maternal Administration of the CNS-Selective Sobetirome Prodrug Sob-AM2 Exerts Thyromimetic Effects in Murine MCT8-Deficient Fetuses
por: Valcárcel-Hernández, Víctor, et al.
Publicado: (2023)

OR01-03 Thyroid Receptor Alpha Interacts with COUP-TFII in the Regulation of Postnatal Skeletal Muscle Regeneration
por: Aguiari, Paola, et al.
Publicado: (2020)

Thyroid hormones regulate both cardiovascular and renal mechanisms underlying hypertension
por: Jankauskas, Stanislovas S., et al.
Publicado: (2020)

Association of thyroid hormones with blood pressure and arterial stiffness in the general population: The Dali study
por: Jamal, Md Tasneem, et al.
Publicado: (2020)

SAT-560 Role of COUP-TFII and Thyroid Hormone Receptor α in Skeletal Muscle Loss
por: Aguiari, Paola, et al.
Publicado: (2019)

Analysis of Hypothalamic TRH Neurons in Regulating Thyroid Hormone Levels
por: Costa e Sousa, Ricardo H, et al.
Publicado: (2021)

Nuclear Receptor Corepressors NCoR1 and SMRT Plays Unique Roles in Central Nervous System
por: Amano, Izuki, et al.
Publicado: (2021)

The Role of Nuclear Receptor Corepressors NCoR1 and SMRT on Physiologic Function in the Adult Mouse
por: Ritter, Megan J, et al.
Publicado: (2021)

iPSC-Derived Human Hepatocytes as a Novel Model to Investigate Thyroid Hormone Action and Signaling
por: De Oliveira, Lorraine Soares, et al.
Publicado: (2021)

SAT-511 Alpha Gal Allergy in a Hypothyroid Patient
por: Slayden, Tanner A, et al.
Publicado: (2020)

Thyroid Hormone Receptor α Mutation Causes a Severe and Thyroxine-Resistant Skeletal Dysplasia in Female Mice
por: Bassett, J. H. Duncan, et al.
Publicado: (2014)

FRI479 Resistance To Thyroid Hormone Due To Thyroid Hormone Receptor Alpha (THRA) Gene Mutation
por: Omar Abdelkarim, Jumana, et al.
Publicado: (2023)

PSAT385 Single Center Experience with the Combination of Lenvatinib and Pembrolizumab for the Treatment of Anaplastic Thyroid Cancer
por: Vodopivec, Danica M, et al.
Publicado: (2022)

Estimabl2: Is There a Need for Radioiodine Ablation in Low Risk Differentiated Thyroid Cancer (DTC) Patients?: Results From the French Randomized Phase III Prospective Trial on 776 Patients (NCT 01837745)
por: Leboulleux, Sophie, et al.
Publicado: (2021)

SAT448 Effects Of Radioactive Iodine Therapy Of Compensated Autonomous Thyroid Nodule After Pharmacological Suppression Of Tsh Secretion
por: Skoczylas, Aleksander, et al.
Publicado: (2023)

MERAIODE: A Redifferentiation Phase II Trial With Trametinib and Dabrafenib Followed by Radioactive Iodine Administration for Metastatic Radioactive Iodine Refractory Differentiated Thyroid Cancer Patients With a BRAFV600E Mutation (NCT 03244956)
por: Leboulleux, Sophie, et al.
Publicado: (2021)

Calcitonin measurement in fine-needle aspirate washouts vs. cytologic examination for diagnosis of primary or metastatic medullary thyroid carcinoma
por: DE CREA, C., et al.
Publicado: (2014)

Aesthetic comparison between synthetic glue and subcuticular sutures in thyroid and parathyroid surgery: a single-blinded randomised clinical trial
por: ALICANDRI-CIUFELLI, M., et al.
Publicado: (2014)

Ultrasonography Diagnosis and Imaging-Based Management of Thyroid Nodules: Revised Korean Society of Thyroid Radiology Consensus Statement and Recommendations
por: Shin, Jung Hee, et al.
Publicado: (2016)

Papillary Thyroid Carcinoma Treated with Radiofrequency Ablation in a Patient with Hypertrophic Cardiomyopathy: A Case Report
por: Sun, Jianyi, et al.
Publicado: (2016)

A Multicenter Prospective Validation Study for the Korean Thyroid Imaging Reporting and Data System in Patients with Thyroid Nodules
por: Ha, Eun Ju, et al.
Publicado: (2016)

Methodology for Developing Evidence-Based Clinical Imaging Guidelines: Joint Recommendations by Korean Society of Radiology and National Evidence-Based Healthcare Collaborating Agency
por: Choi, Sol Ji, et al.
Publicado: (2017)

Core Needle Biopsy of the Thyroid: 2016 Consensus Statement and Recommendations from Korean Society of Thyroid Radiology
por: Na, Dong Gyu, et al.
Publicado: (2017)

Ultrasonographic Interval Changes in Solid Thyroid Nodules after Ultrasonography-Guided Fine-Needle Aspiration
por: Hwang, Ik Jung, et al.
Publicado: (2018)

Efficacy and Safety of Radiofrequency Ablation for Benign Thyroid Nodules: A Prospective Multicenter Study
por: Jung, So Lyung, et al.
Publicado: (2018)

Quality of Life in Patients Treated with Percutaneous Laser Ablation for Non-Functioning Benign Thyroid Nodules: A Prospective Single-Center Study
por: Oddo, Silvia, et al.
Publicado: (2018)

Impact of Nodule Size on Malignancy Risk Differs according to the Ultrasonography Pattern of Thyroid Nodules
por: Hong, Min Ji, et al.
Publicado: (2018)

Complementary Role of Elastography Using Carotid Artery Pulsation in the Ultrasonographic Assessment of Thyroid Nodules: A Prospective Study
por: Hahn, Soo Yeon, et al.
Publicado: (2018)

Columnar Cell Variant of Papillary Thyroid Carcinoma: Ultrasonographic and Clinical Differentiation between the Indolent and Aggressive Types
por: Cho, Jooyeon, et al.
Publicado: (2018)

Computer-Aided Diagnosis of Thyroid Nodules via Ultrasonography: Initial Clinical Experience
por: Yoo, Young Jin, et al.
Publicado: (2018)

2017 Thyroid Radiofrequency Ablation Guideline: Korean Society of Thyroid Radiology
por: Kim, Ji-hoon, et al.
Publicado: (2018)

Primary Imaging Test and Appropriate Biopsy Methods for Thyroid Nodules: Guidelines by Korean Society of Radiology and National Evidence-Based Healthcare Collaborating Agency
por: Ha, Eun Ju, et al.
Publicado: (2018)

Evaluation of Modified Core-Needle Biopsy in the Diagnosis of Thyroid Nodules
por: Ahn, Soomin, et al.
Publicado: (2018)

Ultrasonographic Echogenicity and Histopathologic Correlation of Thyroid Nodules in Core Needle Biopsy Specimens
por: Kim, Ji-hoon, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5q40gs734872u3culqbom7ihr6