Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice

Targeting antigen to surface receptors on dendritic cells (DCs) can improve antibody response against subunit vaccines. We have previously observed that human XCL1-fusion vaccines target murine Xcr1(+) DCs without actively inducing endocytosis of the antigen, resulting in enhanced antibody responses...

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Detalles Bibliográficos
Autores principales: Gudjonsson, Arnar, Andersen, Tor Kristian, Sundvold-Gjerstad, Vibeke, Bogen, Bjarne, Fossum, Even
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533920/
https://www.ncbi.nlm.nih.gov/pubmed/31156636
http://dx.doi.org/10.3389/fimmu.2019.01086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533920/
https://www.ncbi.nlm.nih.gov/pubmed/31156636
http://dx.doi.org/10.3389/fimmu.2019.01086

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