Neuroprotective properties of RT10, a fraction isolated from Parawixia bistriata spider venom, against excitotoxicity injury in neuron-glia cultures

BACKGROUND: L-Glutamate (L-Glu), the major excitatory neurotransmitter in the mammalian Central Nervous System (CNS), is essential to cognitive functions. However, when L-Glu is accumulated in large concentrations at the synaptic cleft, it can induce excitotoxicity that results in secondary damage i...

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Detalles Bibliográficos
Autores principales: Primini, Eduardo Octaviano, Liberato, José Luiz, Fontana, Andreia Cristina Karklin, dos Santos, Wagner Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533932/
https://www.ncbi.nlm.nih.gov/pubmed/31131008
http://dx.doi.org/10.1590/1678-9199-JVATITD-1488-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533932/
https://www.ncbi.nlm.nih.gov/pubmed/31131008
http://dx.doi.org/10.1590/1678-9199-JVATITD-1488-18

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