Single-Cell RNA-Sequencing and Optical Electrophysiology of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Discordance Between Cardiac Subtype-Associated Gene Expression Patterns and Electrophysiological Phenotypes

The ability to accurately phenotype cells differentiated from human induced pluripotent stem cells (hiPSCs) is essential for their application in modeling developmental and disease processes, yet also poses a particular challenge without the context of anatomical location. Our specific objective was...

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Detalles Bibliográficos
Autores principales: Biendarra-Tiegs, Sherri M., Li, Xing, Ye, Dan, Brandt, Emma B., Ackerman, Michael J., Nelson, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Original Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534093/
https://www.ncbi.nlm.nih.gov/pubmed/30892143
http://dx.doi.org/10.1089/scd.2019.0030

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