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Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo pharmacodynamic study

Brimonidine tartrate (BRT) is a hydrophilic α(2) adrenergic agonist used for the treatment of glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring lifetime treatment. Owing to the obstacles facing ocular delivery systems and hydrophilicity of BRT, frequent admi...

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Detalles Bibliográficos
Autores principales:	Emad Eldeeb, Alaa, Salah, Salwa, Ghorab, Mahmoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534210/ https://www.ncbi.nlm.nih.gov/pubmed/31090464 http://dx.doi.org/10.1080/10717544.2019.1609622

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