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Subinhibitory concentrations of Honokiol reduce α-Hemolysin (Hla) secretion by Staphylococcus aureus and the Hla-induced inflammatory response by inactivating the NLRP3 inflammasome

Staphylococcus aureus (S. aureus) is one of the most serious human pathogens. α-Hemolysin (Hla) secreted by S. aureus is a key toxin for various infections. We herein report that Honokiol, a natural plant polyphenol, inhibits the secretion and hemolytic activity of staphylococcal Hla with concomitan...

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Detalles Bibliográficos
Autores principales:	Guo, Na, Liu, Zuojia, Yan, Zhiqiang, Liu, Zonghui, Hao, Kun, Liu, Chuanbo, Wang, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534259/ https://www.ncbi.nlm.nih.gov/pubmed/31119985 http://dx.doi.org/10.1080/22221751.2019.1617643

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